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    <foaf:depiction rdf:resource="http://ja.brc.riken.jp/lab/bpmp/use_photo/mouse/01046.jpg"/>
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    <ns1:donorDNA>mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse activating transcription factor 2 genomic DNA</ns1:donorDNA>
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    <dc:description xml:lang="ja">homoはlethal</dc:description>
    <ns0:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_4"/>
    <dc:description xml:lang="en">ATF2 (CRE-BP1) is a transcription factor of the ATF/CREB family.  This protein has a zinc finger structure as a transactivation domain located at the amino terminus and a leucin zipper motif, and  phosphorylated by the stress-activated protein kinase such as the Jun amino-terminal kinase and p38.  ATF2 deficient mice die shortly after birth and display symptoms of severe respiratory distress with lungs filled with meconium.  This strain is useful as an animal model for meconium aspiration syndrome (MAS).</dc:description>
    <ns1:strainDevelopment xml:lang="ja">開発年：1999年 開発者：前川利男先生 機関名：理化学研究所　分子遺伝学研究室 B6 94%, CBA 6%　10代以上</ns1:strainDevelopment>
    <ns5:resourceTypeLink rdf:resource="http://metadb.riken.jp/terms/xsearch#resource_type_targeting"/>
    <ns0:brs_depositor xml:lang="en">Shunsuke ISHII</ns0:brs_depositor>
    <ns7:SIO_001279 rdf:parseType="Resource">
    </ns7:SIO_001279>
    <ns1:expectedDelivery xml:lang="ja">C（3〜6か月）</ns1:expectedDelivery>
    <ns1:colonyMaintenance xml:lang="en">Backcross to C57BL/6 (Heterozygote x C57BL/6JJcl)</ns1:colonyMaintenance>
    <skos:altLabel xml:lang="ja">ATF2o Knock out (CRE-BP1)-B6</skos:altLabel>
    <skos:altLabel xml:lang="en">ATF2o Knock out (CRE-BP1)-B6</skos:altLabel>
    <ns0:brs_depositorOrganization xml:lang="en">RIKEN</ns0:brs_depositorOrganization>
    <ns5:termsAndConditions xml:lang="en">In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 274, 17813-17819 (1999).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.</ns5:termsAndConditions>
    <ns5:addinfo>&lt;a href='https://brc.riken.jp/mus/pcr01046'&gt;Genotyping protocol -PCR-&lt;/a&gt;</ns5:addinfo>
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    <ns1:ESCellLine>TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]</ns1:ESCellLine>
    <ns0:brs_strainAvailability rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainAvailability_6"/>
    <ns5:application>Cell Biology Research</ns5:application>
    <dcterms:identifier>RBRC01046</dcterms:identifier>
    <ns1:isRecombinant rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean"
    >true</ns1:isRecombinant>
    <ns0:brs_depositor xml:lang="ja">石井　俊輔</ns0:brs_depositor>
    <ns7:SIO_001279 rdf:parseType="Resource">
    </ns7:SIO_001279>
    <ns1:strainDevelopment xml:lang="en">Developed by Drs. Toshio Maekawa and Shunsuke Ishii, RIKEN Tsukuba Institute in 1999.</ns1:strainDevelopment>
    <ns0:brs_hasAppearance rdf:parseType="Resource">
    </ns0:brs_hasAppearance>
    <dcterms:references rdf:resource="http://identifiers.org/pubmed/10364225"/>
    <ns0:brs_depositorOrganization xml:lang="ja">独立行政法人理化学研究所</ns0:brs_depositorOrganization>
    <ns9:RO_0002162 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_10090"/>
    <ns7:SIO_001279 rdf:parseType="Resource">
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    <ns0:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_2"/>
    <ns5:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Approval form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;&lt;A HREF="http://rtcweb.rtc.riken.jp/lab/mg/en/mg.html" target="_blank"&gt;Lab HP&lt;/A&gt;</ns5:addinfo>
    <ns1:colonyMaintenance xml:lang="ja">良好 homoはlethal</ns1:colonyMaintenance>
    <ns1:references rdf:parseType="Resource">
    </ns1:references>
    <ns7:SIO_001279 rdf:parseType="Resource">
    </ns7:SIO_001279>
    <ns0:brs_depositedBy rdf:parseType="Resource">
    </ns0:brs_depositedBy>
    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
    <ns1:colonyMaintenance xml:lang="ja">良好homoはlethal</ns1:colonyMaintenance>
    <ns0:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/straintype_14"/>
    <ns0:brs_strainTypeLink rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainType_17"/>
    <ns11:citesAsAuthority rdf:resource="http://rdf.ncbi.nlm.nih.gov/pubmed/10364225"/>
    <ns7:SIO_001279 rdf:parseType="Resource">
    </ns7:SIO_001279>
    <ns5:termsAndConditions xml:lang="ja">条件を付加する。&lt;br&gt;研究成果の公表にあたって譲渡者の指定する文献を引用する。J. Biol. Chem., 274, 17813-17819 (1999).&lt;br&gt;研究成果の公表にあたって謝辞の表明を必要とする。</ns5:termsAndConditions>
    <ns6:organism rdf:parseType="Resource">
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    <ns1:strainDevelopment xml:lang="ja">開発年：1999年開発者：前川利男先生機関名：理化学研究所　分子遺伝学研究室B6 94%, CBA 6%　10代以上</ns1:strainDevelopment>
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    <ns7:SIO_001279 rdf:parseType="Resource">
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    <foaf:depiction rdf:resource="https://mus.list.brc.riken.jp/ja/wp-content/image_s/01046-P-390-01.jpg"/>
    <ns0:brs_preservationStatus rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/StrainStatus_3"/>
    <ns1:genotypingProtocol rdf:resource="http://mus.brc.riken.jp/DataSheet/pcr01046"/>
    <rdfs:label xml:lang="en">B6.Cg-Atf2&lt;tm1Sis&gt;/Rbrc</rdfs:label>
    <rdfs:label>B6.Cg-Atf2&lt;tm1Sis&gt;/Rbrc</rdfs:label>
    <ns0:brs_hasGenomicFeature rdf:parseType="Resource">
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    <ns0:brs_hasGenomicFeature rdf:parseType="Resource">
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  </rdfs:Class>
  <rdf:Description rdf:about="http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1001888">
    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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  <rdf:Description rdf:about="http://metadb.riken.jp/db/rikenbrc_mouse/RecoveryTestResult_274">
    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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    <ns0:brs_indicatesStrain rdf:resource="http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01046"/>
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